Chenxi Chen

Research Area

Our lab mainly studies the host-pathogen interactions between rice and rice blast fungus, Magnaporthe oryzae, as well as other fungal pathogens. We study whole genome differences and transcriptomes incorporating next generation sequencing and functional characterization of interesting genes by knockout mutagenesis.

Education

• PhD Plant Pathology, The Ohio State University (2013)
• BS Department of Biological Science and Biotechnology (DBSB), Tsinghua University, Beijing, China (2008)

Teaching experience

• Teaching assistant (TA) for Plant Pathology 401: General Plant Pathology, Autumn 2009
• TA for Plant Pathology 600.01: Phytobacteriology, Winter 2012

Awards

• $500, OARDC Professional Development Scholarship, 2012
• 2nd place poster presentation, American Phytopathological Society North Central Division Annual Meeting, Wooster, 2012
• Department of Plant Pathology graduate student fellowship. (2008-present)

Presentations

• Chenxi Chen. Next generation sequencing reveals different gene expression profiles between two strains of Histoplasma capsulatum, poster presentation on Plant and Animal Genome XX, Jan 11-16, 2013, San Diego, CA.
• Chenxi Chen. Revealing pathogenicity in fungal pathogens incorporating next generation sequencing approach. Department seminar, March 2013, Columbus OH.
• Chenxi Chen (2012) Genome-wide transcriptome analysis of two Histoplasma capsulatum strains by RNA-sequencing. Oral presentation plant pathology department seminar.
• Chenxi Chen, Ricardo Almeida, Gustavo Goldman and Thomas Mithcell (2012), Calcium signaling pathway regulates fungal virulence in a similar pattern in human and plant pathogens. Poster presentation, American Phytopathological Society, North Central Division Annual Meeting, Wooster, OH.
• Chenxi Chen, and Thomas Mithcell (2012), Calcium signaling pathway plays an important role in fungal virulence in plants and humans. Poster presentation, Plant and Animal genome XX, San Diego, CA.
• Chenxi Chen, Ricardo Almeida, Gustavo Goldman and Thomas Mithcell (2011), Identify CrzA, the core of calcium signaling pathway, regulated genes by ChIP-sequencing in Aspergillus Fumigatus. Poster presentation, Ohio plant biotechnology consortium, Columbus, OH.
• Chenxi Chen (2011). Identify genes involved in calcium signaling pathway in Aspergillus fumigatus by ChIP-sequencing. Oral presentation, plant pathology department seminar, Columbus OH.
• Chenxi Chen, Ricardo Almeida, Gustavo Goldman and Thomas Mithcell (2011) A Transcription factor CRZA regulated genes identification by ChIP-seq in Aspergillus Fumigatus. Poster presentation, International Plant Pathogenomics Conference, Shenzhen, China.
• Chenxi Chen (2010). Investigate the association of sequence variation and recognition specificity of AvrPiz-t in natural population, oral presentation, plant pathology department seminar.
• Chenxi Chen, Soonok Kim, Thomas Mitchell (2010). Split marker construction for knockout mutagenesis in Magnaporthe oryzae. Poster presentation, Ohio Plant Biotechnology Consortium (OPBC), Columbus, Ohio.
• Chenxi Chen, Soonok Kim, Thomas Mitchell (2009). Analysis of MoCRZ1 downstream genes in Magnaporthe oryzae. Poster presentation, The 101st American Phytopathological Society Annual meeting, Portland, Oregon.
• Chenxi Chen, Soonok Kim, Thomas Mitchell (2009). Regulatory function of MoCRZ1 in calcium/calcineurin signaling pathway in Magnaporthe oryzae. Ohio Plant Biotechnology Consortium (OPBC), Columbus, Ohio.

Activities

• American Phytopathological Society (2008-present)
• Plant Pathology Graduate Student Association (PPGSA)
  Student Representative (2009-2010)

Publications

Jinnan Hu, Chenxi Chen, Tobin Peever, Ha Dang, Christopher Lawrence and Thomas Mitchell. 2012. Genomic characterization of the conditionally dispensable chromosome in Alternaria arborescens provides evidence for horizontal gene transfer. BMC Genomics 13:171.